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Prevention of occlusive coronary artery thrombosis by a murine monoclonal antibody to porcine von Willebrand factor.

A murine monoclonal antibody (mAb) against porcine von Willebrand factor (vWF) induced an antithrombotic state in normal pigs. Thrombosis was induced by a standard procedure of stenosis and mechanical injury of the artery. The mAb was an IgG1 kappa that inhibited vWF-induced platelet aggregation at...

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Autors principals: Bellinger, D A, Nichols, T C, Read, M S, Reddick, R L, Lamb, M A, Brinkhous, K M, Evatt, B L, Griggs, T R
Format: Artigo
Idioma:Inglês
Publicat: 1987
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC299486/
https://ncbi.nlm.nih.gov/pubmed/3120185
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