Interaction of tachykinins with their receptors studied with cyclic analogues of substance P and neurokinin B.

The activities of two groups of cyclic agonists of substance P (SP) have been studied. The disulfide bridge constraints have been designed on the basis of conformational studies on SP and physalaemin indicating an alpha-helical structure for the core of these two tachykinins (group I) and a folding...

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Autors principals: Ploux, O, Lavielle, S, Chassaing, G, Julien, S, Marquet, A, d'Orléans-Juste, P, Dion, S, Regoli, D, Beaujouan, J C, Bergström, L
Format: Artigo
Idioma:Inglês
Publicat: 1987
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC299485/
https://ncbi.nlm.nih.gov/pubmed/2446317
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