Effects of valproic acid on the cell cycle and apoptosis through acetylation of histone and tubulin in a scirrhous gastric cancer cell line

BACKGROUND: Management of peritoneal dissemination is the most critical problem in gastric cancer. This study was performed to investigate the inhibitory effects of valproic acid (VPA) on a highly peritoneal-seeding cell line of human scirrhous gastric cancer, OCUM-2MD3, and to explore the mechanism...

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Bibliografiske detaljer
Main Authors: Yagi, Yasumichi, Fushida, Sachio, Harada, Shinichi, Kinoshita, Jun, Makino, Isamu, Oyama, Katsunobu, Tajima, Hidehiro, Fujita, Hideto, Takamura, Hiroyuki, Ninomiya, Itasu, Fujimura, Takashi, Ohta, Tetsuo, Yashiro, Masakazu, Hirakawa, Kosei
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2994814/
https://ncbi.nlm.nih.gov/pubmed/21080974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-29-149
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