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Effects of Metformin in Experimental Stroke
BACKGROUND AND PURPOSE: AMP-activated protein kinase (AMPK) is an important sensor of energy balance. Stroke-induced AMPK activation is deleterious as both pharmacological inhibition and genetic deletion of AMPK are neuroprotective. Metformin is a known AMPK activator, but reduces stroke incidence i...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2994809/ https://ncbi.nlm.nih.gov/pubmed/20847317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.110.589697 |
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