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NetMHCIIpan-2.0 - Improved pan-specific HLA-DR predictions using a novel concurrent alignment and weight optimization training procedure

BACKGROUND: Binding of peptides to Major Histocompatibility class II (MHC-II) molecules play a central role in governing responses of the adaptive immune system. MHC-II molecules sample peptides from the extracellular space allowing the immune system to detect the presence of foreign microbes from t...

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Détails bibliographiques
Auteurs principaux: Nielsen, Morten, Justesen, Sune, Lund, Ole, Lundegaard, Claus, Buus, Søren
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2994798/
https://ncbi.nlm.nih.gov/pubmed/21073747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-7580-6-9
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