Novel Bioluminescent Quantitative Detection of Nucleic Acid Amplification in Real-Time

BACKGROUND: The real-time monitoring of polynucleotide amplification is at the core of most molecular assays. This conventionally relies on fluorescent detection of the amplicon produced, requiring complex and costly hardware, often restricting it to specialised laboratories. PRINCIPAL FINDINGS: Her...

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Hauptverfasser: Gandelman, Olga A., Church, Vicki L., Moore, Cathy A., Kiddle, Guy, Carne, Christopher A., Parmar, Surendra, Jalal, Hamid, Tisi, Laurence C., Murray, James A. H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2010
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2994769/
https://ncbi.nlm.nih.gov/pubmed/21152399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014155
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