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Evolutionary Innovations and the Organization of Protein Functions in Genotype Space

The organization of protein structures in protein genotype space is well studied. The same does not hold for protein functions, whose organization is important to understand how novel protein functions can arise through blind evolutionary searches of sequence space. In systems other than proteins, t...

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Detalhes bibliográficos
Main Authors: Ferrada, Evandro, Wagner, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2994758/
https://ncbi.nlm.nih.gov/pubmed/21152394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014172
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