Bone Impairment in Phenylketonuria Is Characterized by Circulating Osteoclast Precursors and Activated T Cell Increase

BACKGROUND: Phenylketonuria (PKU) is a rare inborn error of metabolism often complicated by a progressive bone impairment of uncertain etiology, as documented by both ionizing and non- ionizing techniques. METHODOLOGY: Peripheral blood mononuclear cell (PBMC) cultures were performed to study osteocl...

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Autors principals: Roato, Ilaria, Porta, Francesco, Mussa, Alessandro, D'Amico, Lucia, Fiore, Ludovica, Garelli, Davide, Spada, Marco, Ferracini, Riccardo
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2994752/
https://ncbi.nlm.nih.gov/pubmed/21152388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014167
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