Nuclear and Cytoplasmic Accumulation of Ep-ICD Is Frequently Detected in Human Epithelial Cancers

BACKGROUND: We previously demonstrated that nuclear and cytoplasmic accumulation of the intracellular domain (Ep-ICD) of epithelial cell adhesion molecule (EpCAM) accompanied by a reciprocal reduction of its extracellular domain (EpEx), occurs in aggressive thyroid cancers. This study was designed t...

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Autori principali: Ralhan, Ranju, He, Helen C.-H., So, Anthony K.-C., Tripathi, Satyendra C., Kumar, Manish, Hasan, Md. Raghibul, Kaur, Jatinder, Kashat, Lawrence, MacMillan, Christina, Chauhan, Shyam Singh, Freeman, Jeremy L., Walfish, Paul G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2994724/
https://ncbi.nlm.nih.gov/pubmed/21152431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014130
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