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Independent Interactions of Phosphorylated β-Catenin with E-Cadherin at Cell-Cell Contacts and APC at Cell Protrusions

BACKGROUND: The APC tumour suppressor functions in several cellular processes including the regulation of β-catenin in Wnt signalling and in cell adhesion and migration. FINDINGS: In this study, we establish that in epithelial cells N-terminally phosphorylated β-catenin specifically localises to sev...

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Библиографические подробности
Главные авторы: Faux, Maree C., Coates, Janine L., Kershaw, Nadia J., Layton, Meredith J., Burgess, Antony W.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2994709/
https://ncbi.nlm.nih.gov/pubmed/21152425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014127
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