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The Contributions of Interlocking Loops and Extensive Nonlinearity to the Properties of Circadian Clock Models

BACKGROUND: Sensitivity and robustness are essential properties of circadian clock systems, enabling them to respond to the environment but resist noisy variations. These properties should be recapitulated in computational models of the circadian clock. Highly nonlinear kinetics and multiple loops a...

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Autores principales: Saithong, Treenut, Painter, Kevin J., Millar, Andrew J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2994703/
https://ncbi.nlm.nih.gov/pubmed/21152419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013867
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