The effect of phosphorylated Akt inhibition on posterior capsule opacification in an ex vivo canine model

PURPOSE: To evaluate whether inhibition of phosphorylated Akt (pAkt) would reduce or prevent posterior capsule opacification (PCO) in an ex vivo canine lens capsule model. METHODS: Normal and cataractous lenses (n=6) were evaluated for pAkt via immunohistochemistry and immunoblotting. Primary cultur...

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Main Authors: Chandler, Heather L., Webb, Terah R., Barden, Curtis A., Thangavelu, Mirunalni, Kulp, Samuel K., Chen, Ching-Shih, Colitz, Carmen M.H.
Format: Artigo
Sprog:Inglês
Udgivet: Molecular Vision 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2994344/
https://ncbi.nlm.nih.gov/pubmed/21139685
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