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Hypoxia and nickel inhibit histone demethylase JMJD1A and repress Spry2 expression in human bronchial epithelial BEAS-2B cells

Epigenetic silencing of tumor suppressor genes commonly occurs in human cancers via increasing DNA methylation and repressive histone modifications at gene promoters. However, little is known about how pathogenic environmental factors contribute to cancer development by affecting epigenetic regulato...

詳細記述

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書誌詳細
主要な著者: Chen, Haobin, Kluz, Thomas, Zhang, Ronghe, Costa, Max
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2994281/
https://ncbi.nlm.nih.gov/pubmed/20881000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgq197
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