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Thioredoxin and thioredoxin reductase influence estrogen receptor α-mediated gene expression in human breast cancer cells

Accumulation of reactive oxygen species (ROS) in cells damages resident proteins, lipids, and DNA. In order to overcome the oxidative stress that occurs with ROS accumulation, cells must balance free radical production with an increase in the level of antioxidant enzymes that convert free radicals t...

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Autores principales: Rao, Abhi K, Ziegler, Yvonne S, McLeod, Ian X, Yates, John R, Nardulli, Ann M
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2994277/
https://ncbi.nlm.nih.gov/pubmed/19620238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1677/JME-09-0053
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