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Disabled-2 downregulation promotes epithelial-to-mesenchymal transition

BACKGROUND: Metastatic tumour cells are characterised by acquisition of migratory and invasive properties; properties shared by cells, which have undergone epithelial-to-mesenchymal transition (EMT). Disabled-2 (Dab2) is a putative tumour suppressor whose expression has been shown to be downregulate...

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Detalles Bibliográficos
Main Authors: Martin, J C, Herbert, B-S, Hocevar, B A
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2994233/
https://ncbi.nlm.nih.gov/pubmed/21063401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605975
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