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The epidermal growth factor receptor family in breast cancer

The human epidermal growth factor receptor (HER) family comprises four homologous members: EGFR, HER-2, HER-3, and HER-4. The activation of these receptors triggers a complex series of signal transduction pathways which affect pivotal tumorigenic processes. The deregulation of HER signaling is seen...

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Detalhes bibliográficos
Main Authors: Koutras, Angelos K, Evans, T R Jeffry
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2994209/
https://ncbi.nlm.nih.gov/pubmed/21127748
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