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The epidermal growth factor receptor family in breast cancer
The human epidermal growth factor receptor (HER) family comprises four homologous members: EGFR, HER-2, HER-3, and HER-4. The activation of these receptors triggers a complex series of signal transduction pathways which affect pivotal tumorigenic processes. The deregulation of HER signaling is seen...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Dove Medical Press
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2994209/ https://ncbi.nlm.nih.gov/pubmed/21127748 |
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