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Refining targeted therapies in chronic myeloid leukemia: development and application of nilotinib, a step beyond imatinib

The BCR-ABL kinase inhibitor imatinib mesylate is currently the standard therapy for patients with chronic myeloid leukemia (CML). Despite the remarkable results achieved with imatinib for the treatment of CML, the emergence of resistance to this drug has become a significant problem. Mutations with...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Breccia, Massimo, Alimena, Giuliana
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Dove Medical Press 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2994207/
https://ncbi.nlm.nih.gov/pubmed/21127752
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