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RNAs actively cycle on the Sm-like protein Hfq

Hfq, a protein required for small RNA (sRNA)-mediated regulation in bacteria, binds RNA with low-nanomolar K(d) values and long half-lives of complexes (>100 min). This cannot be reconciled with the 1- 2-min response time of regulation in vivo. We show that RNAs displace each other on Hfq on a sh...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Fender, Aurélie, Elf, Johan, Hampel, Kornelia, Zimmermann, Bastian, Wagner, E. Gerhart H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2994036/
https://ncbi.nlm.nih.gov/pubmed/21123649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.591310
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