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In Vivo Activation of the Intracrine Vitamin D Pathway in Innate Immune Cells and Mammary Tissue during a Bacterial Infection

Numerous in vitro studies have shown that toll-like receptor signaling induces 25-hydroxyvitamin D(3) 1α-hydroxylase (1α-OHase; CYP27B1) expression in macrophages from various species. 1α-OHase is the primary enzyme that converts 25-hydroxyvitamin D(3) to 1,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3))...

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Hlavní autoři: Nelson, Corwin D., Reinhardt, Timothy A., Beitz, Donald C., Lippolis, John D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993969/
https://ncbi.nlm.nih.gov/pubmed/21124742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015469
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