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Pyrvinium, a Potent Small Molecule Wnt Inhibitor, Promotes Wound Repair and Post-MI Cardiac Remodeling

Wnt signaling plays an important role in developmental and stem cell biology. To test the hypothesis that temporary inhibition of Wnt signaling will enhance granulation tissue and promote angiogenesis in tissue repair, we employed a recently characterized small molecule Wnt inhibitor. Pyrvinium is a...

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Autori principali: Saraswati, Sarika, Alfaro, Maria P., Thorne, Curtis A., Atkinson, James, Lee, Ethan, Young, Pampee P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993965/
https://ncbi.nlm.nih.gov/pubmed/21170416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015521
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