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Pyrvinium, a Potent Small Molecule Wnt Inhibitor, Promotes Wound Repair and Post-MI Cardiac Remodeling

Wnt signaling plays an important role in developmental and stem cell biology. To test the hypothesis that temporary inhibition of Wnt signaling will enhance granulation tissue and promote angiogenesis in tissue repair, we employed a recently characterized small molecule Wnt inhibitor. Pyrvinium is a...

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Détails bibliographiques
Auteurs principaux: Saraswati, Sarika, Alfaro, Maria P., Thorne, Curtis A., Atkinson, James, Lee, Ethan, Young, Pampee P.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993965/
https://ncbi.nlm.nih.gov/pubmed/21170416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015521
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