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Neuronal Transcriptional Repressor REST Suppresses an Atoh7-Independent Program for Initiating Retinal Ganglion Cell Development

As neuronal progenitors differentiate into neurons, they acquire a unique set of transcription factors. The transcriptional repressor REST prevents progenitors from undergoing differentiation. Notably, REST binding sites are often associated with retinal ganglion cell (RGC) genes whose expression in...

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Autors principals: Mao, Chai-An, Tsai, Wen-Wei, Cho, Jang-Hyeon, Pan, Ping, Barton, Michelle Craig, Klein, William H.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993882/
https://ncbi.nlm.nih.gov/pubmed/20969844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2010.10.008
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