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Complement regulates TLR4-mediated inflammatory responses during intestinal ischemia reperfusion

Innate immune responses including TLR4 and complement activation are required for mesenteric ischemia/reperfusion (IR)-induced tissue damage. We examined the regulation of TLR4 and complement activation in a mouse model of intestinal IR. Intestinal IR induced C3 deposition in a TLR4 dependent manner...

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Detalhes bibliográficos
Main Authors: Pope, Michael R., Hoffman, Sara M., Tomlinson, Stephen, Fleming, Sherry D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993765/
https://ncbi.nlm.nih.gov/pubmed/20800895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2010.07.004
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