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Oxysterol Binding Protein-dependent Activation of Sphingomyelin Synthesis in the Golgi Apparatus Requires Phosphatidylinositol 4-Kinase IIα

Cholesterol and sphingomyelin (SM) associate in raft domains and are metabolically coregulated. One aspect of coordinate regulation occurs in the Golgi apparatus where oxysterol binding protein (OSBP) mediates sterol-dependent activation of ceramide transport protein (CERT) activity and SM synthesis...

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Detalhes bibliográficos
Main Authors: Banerji, Sangeeta, Ngo, Mike, Lane, Ciaran F., Robinson, Carolyn-Ann, Minogue, Shane, Ridgway, Neale D.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993743/
https://ncbi.nlm.nih.gov/pubmed/20881054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E10-05-0424
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