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The Roles of Two Distinct Regions of PINCH-1 in the Regulation of Cell Attachment and Spreading

Cells attach to the extracellular matrix (ECM) through integrins to form focal adhesion complexes, and this process is followed by the extension of lamellipodia to enable cell spreading. PINCH-1, an adaptor protein essential for the regulation of cell–ECM adhesion, consists of five tandem LIM domain...

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Detalhes bibliográficos
Main Authors: Ito, Satoko, Takahara, Yuko, Hyodo, Toshinori, Hasegawa, Hitoki, Asano, Eri, Hamaguchi, Michinari, Senga, Takeshi
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993741/
https://ncbi.nlm.nih.gov/pubmed/20926685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E10-05-0459
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