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Quantification and deconvolution of asymmetric LC-MS peaks using the bi-Gaussian mixture model and statistical model selection
BACKGROUND: Liquid chromatography-mass spectrometry (LC-MS) is one of the major techniques for the quantification of metabolites in complex biological samples. Peak modeling is one of the key components in LC-MS data pre-processing. RESULTS: To quantify asymmetric peaks with high noise level, we dev...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2993707/ https://ncbi.nlm.nih.gov/pubmed/21073736 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-559 |
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