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Mantle cell lymphoma activation enhances bortezomib sensitivity

Patients with mantle cell lymphoma (MCL) typically respond to initial treatment but subsequently relapse. This pattern suggests that a population of MCL cells is both drug resistant and capable of clonogenic growth. The intracellular enzyme retinaldehyde dehydrogenase (ALDH) provides resistance to s...

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Bibliografiske detaljer
Main Authors: Brennan, Sarah K., Meade, Brooke, Wang, Qiuju, Merchant, Akil A., Kowalski, Jeanne, Matsui, William
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993624/
https://ncbi.nlm.nih.gov/pubmed/20570863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-02-268375
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