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Can we build it better? Using BAC genetics to engineer more effective cytomegalovirus vaccines
The magnitude and durability of immunity to human cytomegalovirus (HCMV) following natural infection is compromised by the presence of immune modulation genes that appear to promote evasion of host clearance mechanisms. Since immunity to HCMV offers limited protection, rational design of effective v...
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Clinical Investigation
2010
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2993604/ https://ncbi.nlm.nih.gov/pubmed/21099107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI45250 |
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