Recombinant mouse cytomegalovirus expressing a ligand for the NKG2D receptor is attenuated and has improved vaccine properties

Human CMV (HCMV) is a major cause of morbidity and mortality in both congenitally infected and immunocompromised individuals. Development of an effective HCMV vaccine would help protect these vulnerable groups. NK group 2, member D (NKG2D) is a potent activating receptor expressed by cells of the in...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Slavuljica, Irena, Busche, Andreas, Babić, Marina, Mitrović, Maja, Gašparović, Iva, Cekinović, Đurđica, Markova Car, Elitza, Pernjak Pugel, Ester, Ciković, Ana, Lisnić, Vanda Juranić, Britt, William J., Koszinowski, Ulrich, Messerle, Martin, Krmpotić, Astrid, Jonjić, Stipan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2010
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993599/
https://ncbi.nlm.nih.gov/pubmed/21099111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI43961
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