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Geminin deletion from hematopoietic cells causes anemia and thrombocytosis in mice

HSCs maintain the circulating blood cell population. Defects in the orderly pattern of hematopoietic cell division and differentiation can lead to leukemia, myeloproliferative disorders, or marrow failure; however, the factors that control this pattern are incompletely understood. Geminin is an unst...

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Detalhes bibliográficos
Main Authors: Shinnick, Kathryn M., Eklund, Elizabeth A., McGarry, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993593/
https://ncbi.nlm.nih.gov/pubmed/21041951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI43556
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