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Geminin deletion from hematopoietic cells causes anemia and thrombocytosis in mice

HSCs maintain the circulating blood cell population. Defects in the orderly pattern of hematopoietic cell division and differentiation can lead to leukemia, myeloproliferative disorders, or marrow failure; however, the factors that control this pattern are incompletely understood. Geminin is an unst...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Shinnick, Kathryn M., Eklund, Elizabeth A., McGarry, Thomas J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993593/
https://ncbi.nlm.nih.gov/pubmed/21041951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI43556
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