Whole-genome sequencing and microarray analysis of ex vivo Plasmodium vivax reveal selective pressure on putative drug resistance genes

Plasmodium vivax causes 25–40% of malaria cases worldwide, yet research on this human malaria parasite has been neglected. Nevertheless, the recent publication of the P. vivax reference genome now allows genomics and systems biology approaches to be applied to this pathogen. We show here that whole-...

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Hoofdauteurs: Dharia, Neekesh V., Bright, A. Taylor, Westenberger, Scott J., Barnes, S. Whitney, Batalov, Serge, Kuhen, Kelli, Borboa, Rachel, Federe, Glenn C., McClean, Colleen M., Vinetz, Joseph M., Neyra, Victor, Llanos-Cuentas, Alejandro, Barnwell, John W., Walker, John R., Winzeler, Elizabeth A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2010
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993397/
https://ncbi.nlm.nih.gov/pubmed/21037109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1003776107
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