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Ivermectin disrupts the function of the excretory-secretory apparatus in microfilariae of Brugia malayi
Ivermectin (IVM) is a broad-spectrum anthelmintic used in filariasis control programs. By binding to nematode glutamate-gated chloride channels (GluCls), IVM disrupts neurotransmission processes regulated by GluCl activity. IVM treatment of filarial infections is characterized by an initial dramatic...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2993382/ https://ncbi.nlm.nih.gov/pubmed/21041637 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1011983107 |
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