Autocrine TGF-β and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts

Much interest is currently focused on the emerging role of tumor-stroma interactions essential for supporting tumor progression. Carcinoma-associated fibroblasts (CAFs), frequently present in the stroma of human breast carcinomas, include a large number of myofibroblasts, a hallmark of activated fib...

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Detalhes bibliográficos
Main Authors: Kojima, Yasushi, Acar, Ahmet, Eaton, Elinor Ng, Mellody, Kieran T., Scheel, Christina, Ben-Porath, Ittai, Onder, Tamer T., Wang, Zhigang C., Richardson, Andrea L., Weinberg, Robert A., Orimo, Akira
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993333/
https://ncbi.nlm.nih.gov/pubmed/21041659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1013805107
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