Loss of Heterozygosity and DNA Methylation Affect Germline Fibroblast Growth Factor Receptor 4 Polymorphism to Direct Allelic Selection in Breast Cancer

Genome-wide association studies highlight the importance of the fibroblast growth factor (FGF) receptor as a risk factor for breast cancer development. In particular, FGFR4 has been implicated in membrane ruffling, cancer cell invasiveness, and clinical chemoresistance in breast cancer. In this work...

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Main Authors: Zhu, Xuegong, Zheng, Lei, Asa, Sylvia L., Ezzat, Shereen
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2010
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Regular Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993303/
https://ncbi.nlm.nih.gov/pubmed/21037081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.100509
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