Leptin Receptor Signaling Supports Cancer Cell Metabolism through Suppression of Mitochondrial Respiration in Vivo

Obesity represents a risk factor for certain types of cancer. Leptin, a hormone predominantly produced by adipocytes, is elevated in the obese state. In the context of breast cancer, leptin derived from local adipocytes is present at high concentrations within the mammary gland. A direct physiologic...

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Bibliografiske detaljer
Main Authors: Park, Jiyoung, Kusminski, Christine M., Chua, Streamson C., Scherer, Philipp E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2010
Fag:
Regular Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993284/
https://ncbi.nlm.nih.gov/pubmed/21056997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.100595
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