Combination Therapy with Epigallocatechin-3-Gallate and Doxorubicin in Human Prostate Tumor Modeling Studies : Inhibition of Metastatic Tumor Growth in Severe Combined Immunodeficiency Mice

The polyphenol epigallocatechin-3-gallate (EGCG) in combination with doxorubicin (Dox) exhibits a synergistic activity in blocking the growth and colony-forming ability of human prostate cell lines in vitro. EGCG has been found to disrupt the mitochondrial membrane potential, induce vesiculation of...

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Detalhes bibliográficos
Main Authors: Stearns, Mark E., Amatangelo, Michael D., Varma, Devika, Sell, Chris, Goodyear, Shaun M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993277/
https://ncbi.nlm.nih.gov/pubmed/20971741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.100330
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