Effects of Hypoxia-Inducible Factor-1α Overexpression in Pregnant Mice : Possible Implications for Preeclampsia and Intrauterine Growth Restriction

Preeclampsia and intrauterine growth restriction (IUGR) are pregnancy-specific disorders that share a common pathophysiology. Hypoxia-inducible factor-1α (HIF-1α) is a transcription factor that plays an important role in placental development. HIF-1α is elevated in preeclamptic placentas and induces...

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Main Authors: Tal, Reshef, Shaish, Aviv, Barshack, Iris, Polak-Charcon, Silvia, Afek, Arnon, Volkov, Alexander, Feldman, Boris, Avivi, Camila, Harats, Dror
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993274/
https://ncbi.nlm.nih.gov/pubmed/20952590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090800
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