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Identification of a vaccinia virus gene encoding a type I DNA topoisomerase.

Vaccinia virus encapsidates a type I DNA topoisomerase (EC 5.99.1.2). The enzyme was purified from virus cores to apparent homogeneity, yielding a protein of Mr 32,000. The amino-terminal sequence of the isolated Mr 32,000 polypeptide was determined and used to map the putative structural gene for t...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Shuman, S, Moss, B
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1987
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299319/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2823264/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.21.7478
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