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Isolation of periportal, midlobular, and centrilobular rat liver sinusoidal endothelial cells enables study of zonated drug toxicity

Many liver sinusoidal endothelial cell (LSEC)-dependent processes, including drug-induced liver injury, ischemia-reperfusion injury, acute and chronic rejection, fibrosis, and the HELLP (hemolytic anemia, elevated liver enzymes, low platelet count) syndrome, may have a lobular distribution. Studies...

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Detalhes bibliográficos
Main Authors: Xie, Guanhua, Wang, Lin, Wang, Xiangdong, Wang, Lei, DeLeve, Laurie D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993174/
https://ncbi.nlm.nih.gov/pubmed/20813915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00302.2010
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