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mTOR-Mediated Activation of p70 S6K Induces Differentiation of Pluripotent Human Embryonic Stem Cells

Deciding to exit pluripotency and undergo differentiation is of singular importance for pluripotent cells, including embryonic stem cells (ESCs). The molecular mechanisms for these decisions to differentiate, as well as reversing those decisions during induced pluripotency (iPS), have focused largel...

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Detalles Bibliográficos
Main Authors: Easley, Charles A., Ben-Yehudah, Ahmi, Redinger, Carrie J., Oliver, Stacie L., Varum, Sandra T., Eisinger, Vonya M., Carlisle, Diane L., Donovan, Peter J., Schatten, Gerald P.
Formato: Artigo
Idioma:Inglês
Publicado: Mary Ann Liebert, Inc. 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993047/
https://ncbi.nlm.nih.gov/pubmed/20698768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cell.2010.0011
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