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ROCK Inhibition Facilitates the Generation of Human-Induced Pluripotent Stem Cells in a Defined, Feeder-, and Serum-Free System

Human-induced pluripotent stem cells (iPSCs) generated from human adult somatic cells through reprogramming hold great promises for future regenerative medicine. However, exposure of human iPSCs to animal feeder and serum in the process of their generation and maintenance imposes risk of transmittin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lai, Wing-Hon, Ho, Jenny Chung-Yee, Lee, Yee-Ki, Ng, Kwong-Man, Au, Ka-Wing, Chan, Yau-Chi, Lau, Chu-Pak, Tse, Hung-Fat, Siu, Chung-Wah
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993021/
https://ncbi.nlm.nih.gov/pubmed/20858051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cell.2010.0051
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