ROCK Inhibition Facilitates the Generation of Human-Induced Pluripotent Stem Cells in a Defined, Feeder-, and Serum-Free System

Human-induced pluripotent stem cells (iPSCs) generated from human adult somatic cells through reprogramming hold great promises for future regenerative medicine. However, exposure of human iPSCs to animal feeder and serum in the process of their generation and maintenance imposes risk of transmittin...

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Autores principales: Lai, Wing-Hon, Ho, Jenny Chung-Yee, Lee, Yee-Ki, Ng, Kwong-Man, Au, Ka-Wing, Chan, Yau-Chi, Lau, Chu-Pak, Tse, Hung-Fat, Siu, Chung-Wah
Formato: Artigo
Lenguaje:Inglês
Publicado: Mary Ann Liebert, Inc. 2010
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993021/
https://ncbi.nlm.nih.gov/pubmed/20858051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cell.2010.0051
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