Quercetin potentiates insulin secretion and protects INS-1 pancreatic β-cells against oxidative damage via the ERK1/2 pathway

BACKGROUND AND PURPOSE: Quercetin lowers plasma glucose, normalizes glucose tolerance tests and preserves pancreatic β-cell integrity in diabetic rats. However, its mechanism of action has never been explored in insulin-secreting β-cells. Using the INS-1 β-cell line, the effects of quercetin were de...

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Detalhes bibliográficos
Main Authors: Youl, E, Bardy, G, Magous, R, Cros, G, Sejalon, F, Virsolvy, A, Richard, S, Quignard, JF, Gross, R, Petit, P, Bataille, D, Oiry, C
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2010
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992896/
https://ncbi.nlm.nih.gov/pubmed/20860660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.00910.x
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