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SirA enforces diploidy by inhibiting the replication initiator DnaA during spore formation in Bacillus subtilis

How cells maintain their ploidy is relevant to cellular development and disease. Here, we investigate the mechanism by which the bacterium Bacillus subtilis enforces diploidy as it differentiates into a dormant spore. We demonstrate that a sporulation-induced protein SirA (originally annotated YneE)...

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Main Authors: Wagner, Jennifer K., Marquis, Kathleen A., Rudner, David Z.
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992877/
https://ncbi.nlm.nih.gov/pubmed/19682252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2009.06825.x
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