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SirA enforces diploidy by inhibiting the replication initiator DnaA during spore formation in Bacillus subtilis

How cells maintain their ploidy is relevant to cellular development and disease. Here, we investigate the mechanism by which the bacterium Bacillus subtilis enforces diploidy as it differentiates into a dormant spore. We demonstrate that a sporulation-induced protein SirA (originally annotated YneE)...

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Библиографические подробности
Главные авторы: Wagner, Jennifer K., Marquis, Kathleen A., Rudner, David Z.
Формат: Artigo
Язык:Inglês
Опубликовано: 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992877/
https://ncbi.nlm.nih.gov/pubmed/19682252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2009.06825.x
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