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Structural analysis of the interaction between Dishevelled2 and clathrin AP-2 adaptor, a critical step in non-canonical Wnt signaling

Wnt association with its receptor, Frizzled (Fz), and recruitment by the latter of an adaptor, Dishevelled (Dvl), initiates signaling through at least two distinct pathways (“canonical” and “non-canonical”). Endocytosis and compartmentalization help determine the signaling outcome. Our previous work...

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Bibliografiska uppgifter
Huvudupphovsmän: Yu, Anan, Xing, Yi, Harrison, Stephen C., Kirchhausen, Tomas
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992793/
https://ncbi.nlm.nih.gov/pubmed/20947020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2010.07.010
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