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Structural analysis of the interaction between Dishevelled2 and clathrin AP-2 adaptor, a critical step in non-canonical Wnt signaling

Wnt association with its receptor, Frizzled (Fz), and recruitment by the latter of an adaptor, Dishevelled (Dvl), initiates signaling through at least two distinct pathways (“canonical” and “non-canonical”). Endocytosis and compartmentalization help determine the signaling outcome. Our previous work...

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Hlavní autoři: Yu, Anan, Xing, Yi, Harrison, Stephen C., Kirchhausen, Tomas
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992793/
https://ncbi.nlm.nih.gov/pubmed/20947020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2010.07.010
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