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Protein structure analysis of mutations causing inheritable diseases. An e-Science approach with life scientist friendly interfaces

BACKGROUND: Many newly detected point mutations are located in protein-coding regions of the human genome. Knowledge of their effects on the protein's 3D structure provides insight into the protein's mechanism, can aid the design of further experiments, and eventually can lead to the devel...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Venselaar, Hanka, te Beek, Tim AH, Kuipers, Remko KP, Hekkelman, Maarten L, Vriend, Gert
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992548/
https://ncbi.nlm.nih.gov/pubmed/21059217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-548
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