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Uncultured Marrow Mononuclear Cells Delivered Within Fibrin Glue Hydrogels to Porous Scaffolds Enhance Bone Regeneration Within Critical-Sized Rat Cranial Defects

For bone tissue engineering, the benefits of incorporating mesenchymal stem cells (MSCs) into porous scaffolds are well established. There is, however, little consensus on the effects of or need for MSC handling ex vivo. Culture and expansion of MSCs adds length and cost, and likely increases risk a...

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Main Authors: Kretlow, James D., Spicer, Patrick P., Jansen, John A., Vacanti, Charles A., Kasper, F. Kurtis, Mikos, Antonios G.
Format: Artigo
Jezik:Inglês
Izdano: Mary Ann Liebert, Inc. 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992452/
https://ncbi.nlm.nih.gov/pubmed/20715884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ten.tea.2010.0471
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