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Isolation of osteogenin, an extracellular matrix-associated, bone-inductive protein, by heparin affinity chromatography.

Implantation of demineralized diaphyseal bone matrix in subcutaneous sites induces a sequence of events resulting in the local differentiation of endochondral bone. Demineralized bovine bone matrix was dissociatively extracted in 4.0 M guanidine hydrochloride and the bone-inductive proteins were pur...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Sampath, T K, Muthukumaran, N, Reddi, A H
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299239/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3478684/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.20.7109
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