Functional role of gangliotetraosylceramide in epithelial-to-mesenchymal transition process induced by hypoxia and by TGF-β

The epithelial-to-mesenchymal transition (EMT) is a basic cellular process that plays a key role in normal embryonic development and in cancer progression/metastasis. Our previous study indicated that EMT processes of mouse and human epithelial cells induced by TGF-β display clear reduction of gangl...

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Bibliographic Details
Main Authors: Guan, Feng, Schaffer, Lana, Handa, Kazuko, Hakomori, Sen-itiroh
Format: Artigo
Language:Inglês
Published: Federation of American Societies for Experimental Biology 2010
Subjects:
Research Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992377/
https://ncbi.nlm.nih.gov/pubmed/20720159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-162107
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