Interactions of STAP-2 with Brk and STAT3 Participate in Cell Growth of Human Breast Cancer Cells

STAP-2 (signal transducing adaptor protein-2) is a recently identified adaptor protein that contains pleckstrin homology (PH) and Src homology 2-like domains, as well as a STAT3-binding motif in its C-terminal region. STAP-2 is also a substrate of breast tumor kinase (Brk). In breast cancers, Brk ex...

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Detalhes bibliográficos
Main Authors: Ikeda, Osamu, Sekine, Yuichi, Mizushima, Akihiro, Nakasuji, Misa, Miyasaka, Yuto, Yamamoto, Chikako, Muromoto, Ryuta, Nanbo, Asuka, Oritani, Kenji, Yoshimura, Akihiko, Matsuda, Tadashi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992243/
https://ncbi.nlm.nih.gov/pubmed/20929863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.162388
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